RewriteRule ^([^.]+)/([^.]+)/([^.]+)$ blog/index.php?page=$1&sef=$2&blog_ID=$3 [L,QSA]

<?php
function seo($s) {
    $tr = array('ş','Ş','ı','I','İ','ğ','Ğ','ü','Ü','ö','Ö','Ç','ç','(',')','/',' ',',','?');
    $eng = array('s','s','i','i','i','g','g','u','u','o','o','c','c','','','-','-','','');
    $s = str_replace($tr,$eng,$s);
    $s = strtolower($s);
    $s = preg_replace('/&amp;amp;amp;amp;amp;amp;amp;amp;amp;.+?;/', '', $s);
    $s = preg_replace('/\s+/', '-', $s);
    $s = preg_replace('|-+|', '-', $s);
    $s = preg_replace('/#/', '', $s);
    $s = str_replace('.', '', $s);
    $s = trim($s, '-');
    return $s;
}

?>

<a href="blog/<?=seo($blog["blog_baslik"]).'/'.$blog["id"]?>">

RewriteRule ^blog/([0-9a-zA-Z-_]+)/([0-9]+)? blog.php?id=$2 [L,QSA]